“ Everything About Skin Cancer: Causes, Prevention, and Breakthrough Treatments”

 

Skin cancer is the most common form of cancer globally, with millions affected each year. The three main types are basal cell carcinoma, squamous cell carcinoma, and melanoma—the deadliest form. Melanoma is less common but responsible for the majority of skin cancer-related deaths. The leading cause is ultraviolet (UV) radiation from the sun and tanning beds. Genetics, skin type, and previous sunburns also increase the risk.


Preventing skin cancer starts with sun safety. Daily use of a broad-spectrum sunscreen with SPF 30 or higher, staying in the shade during peak sun hours, and wearing protective clothing can help significantly reduce the risk. It’s also important to check your skin regularly. Any mole that changes in shape, color, or size should be seen by a doctor. Early detection is crucial—when melanoma is caught early, the five-year survival rate can be as high as 99%.


Recent advances in technology are making diagnosis faster and more accurate. Artificial intelligence is now used to analyze skin lesions, and handheld scanners can help detect cancer earlier than ever before. Some health systems, like the NHS in the UK, are already using AI tools to offer instant skin checks.


Treatments are also improving. Immunotherapies, including newly approved TIL cell therapy like Lifileucel, are showing strong long-term results in treating advanced melanoma. Cancer vaccines like Moderna’s mRNA-4157 are reducing recurrence and increasing survival rates. Other experimental therapies include oncolytic viruses that target cancer cells and leave healthy tissue unharmed, and topical immunotherapies that can prevent or treat early skin lesions.


Even common medications like metformin, typically used for diabetes, are now being studied for their ability to reduce skin cancer risk. With continued research, more effective and less invasive treatments are becoming available, giving hope to those affected by skin cancer.



References

  • Global AI detection accuracy, UV link, cancer stats
  • Canada melanoma trends & sunscreen use  
  • Personal story: early melanoma detection
  • AI diagnostics in NHS & Scotland  
  • Liquid biopsy for cancer  
  • Lifileucel approval & TIL stats  
  • Checkpoint inhibitor breakthroughs  
  • Topical immunotherapy & sunspot reduction  
  • TVEC virus therapy in BCC  
  • mRNA vaccine results
  • Metformin linked to non‑melanoma risk reduction  



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